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A Journal on Surgery
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,877
Minerva Chirurgica 2005 February;60(1):17-22
The choice of surgical therapy into adenocarcinoma of the cardia
Solerio D., Camandona M., Gasparri G., Casalegno P. A., Raggio E., Dei Poli M.
Aim. From 1996 the adenocarcinoma of the esophago-gastric junction (AEG) is divided into 3 types according to Siewert¹s classification. For AEG type I and III the surgical treatment is codified, while for type II is still controversial. The aim of our study is understand what is the better surgical treatment for AEG type II.
Methods. From 1990 to 2002 we have performed 111 resection for adenocarcinoma of the cardia: 25 for AEG type I (all esophago-gastric resection), 39 for type II (22 esophago-gastric resection, 17 extended total gastrectomy with esophageal resection) and 47 for type III (8 esophago-gastric resection, 39 extended total gastrectomy with esophageal resection).
Results. The morbility and mortality rates are 17 and 5.4%, without significant difference between the different surgical treatment (p>0.01). The 5 year survival rate is 35%. Significant prognostic factors are the staging TNM (p=0.002) and principally the presence of metastatic lymph nodes (p=0.001). For AEG type II any significant difference in survival is associated with surgical strategy, also in early stage (p>0.01).
Conclusion. According to the results of our study and those of the other authors, who have showed that a 10 cm distance of the neoplasm by the gastric side and the esophageal one could assure oncologic radicality and also that metastatic lymph nodes below pylorus and near greater curvature are uncommon, we can consider esophago-gastric resection for AEG II a speed, safe and oncologically correct surgical treatment.