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Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,877
Online ISSN 1827-1626
Schietroma M., Lattanzio R., Risetti A., Di Placido R., Carlei F., Leardi S., Mattucci S., Bellucci N., Pistoia M. A., Simi M.
Background. Acute biliary pancreatitis (ABP) still retains high morbidity (15-50%) and mortality (20-35%). Therefore it appears to be crucial to clearly assess the aetiological factors (50% of idiopathic are in fact biliary pancreatitis) and to establish the severity in order to plan the appropriate treatment.
Methods. In this study we have considered 61 patients divided into 2 groups. Group 1 had 29 ABP patients aging less than 65 years, group 2 32 patients aging more than 65 years; the diagnosis was made by ultrasound and serological values in 78.5% of cases, while in the remaing 21.5% was only serological. Following Ranson and APACHE II scoring 18 cases (29.5%) were classified as severe [6 (20.6%) in group 1; 12 (37.5%) in group 2: p<0.01], 43 (70.4%) as mild. All patients with severe ABP had emergency ERCP+ES (within 24-48 hrs) followed by LC (&Mac178;10 days). Patients with mild ABP had LC within 10 days; in these cases IOC was always done.
Results. In severe cases operative endoscopy cured pancreatic inflammation in 13 cases. Subsequent LC never showed serious morbidity, apart subcutaneous emphysema in one case. In 5 cases laparotomy was required since pancreatic necrosis was present, with 60% mortality. In patients with mild pancreatitis LC was successfully performed in all cases, with 6.9% morbidity. IOC showed choledochal stones in 32.5% of cases, while in severe cases stones in the biliary tree were showed in 88.8% of cases. No significant differences were detected between group 1 and 2.
Conclusions. In conclusion ABP treatment is always surgical, and almost always with minimally-invasive procedures in severe cases (ERCP+ES with LC &Mac178;10 days) if surgery is performed within 24-48 hrs as well as in mild cases (LC+IOC) when surgery is done within 10 days, independently from the age of the patients.