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A Journal on Heart and Vascular Diseases
Official Journal of the Italian Society of Angiology and Vascular Pathology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,752
Minerva Cardioangiologica 2016 August;64(4):367-74
The relationship between culprit artery and the clinical outcomes in patients undergoing primary percutaneous coronary ıntervention for ınferior wall ST segment elevation myocardial ınfarction
Erkan AYHAN 1, Turgay ISİK 2, Bahman GHANNADİAN 3, Ozgur AKGÜL 4, Nermina ALAGİC 4 ✉
1 Department of Cardiology, Medical Park Hospital, Bursa, Turkey; 2 Balıkesir University, School of Medicine, Balikesir, Turkey; 3 Department of Cardiology, California University, School of Medicine, San Diego, CA, USA; 4 Department of Cardiology Mehmet Akif Ersoy Education and Research Hospital, Istanbul, Turkey
BACKGROUND: We observed the effect of culprit artery in patients undergoing primary percutaneous coronary intervention (PCI) caused by inferior wall ST elevation myocardial infarction (STEMI) during hospital stay and 6-month follow-ups.
METHODS: After exclusion, 233 consecutive patients with inferior wall STEMI (mean age: 55.6±12.4 years) undergoing primary PCI were prospectively enrolled in this study. Patients were divided into two groups according to culprit artery: right coronary artery (RCA=group 1 [N.=187]) and left circumflex artery (LCX=group 2 [N.=46]). Patients were followed up for six months.
RESULTS: Patients of both groups had similar risk factors such as age, sex, hypertension and diabetes mellitus. While there were more cases of right ventricular infarction (P=0.001), complete atrioventricular block (P=0.002) and proximal located lesions (P=0.002) in RCA group, there was less collateral circulation incidence in LCX group (P=0.04). Ratios of no-reflow and myocardial blush grade after primary PCI were similiar in both groups. There was no significant difference between groups associated with major adverse cardiac events (MACE), target-vessel revascularization and mortality ratios during hospital stay and 6-month follow-up period.
CONCLUSIONS: The impact of RCA and LCX on MACE and cardiovascular mortality during hospital stay and the 6-month follow-up (mid-term) period are similar in patients on whom primary PCI was performed due to inferior wall STEMI.