Home > Journals > Minerva Cardioangiologica > Past Issues > Minerva Cardioangiologica 2011 February;59(1) > Minerva Cardioangiologica 2011 February;59(1):31-8

CURRENT ISSUE
 

ARTICLE TOOLS

Reprints

MINERVA CARDIOANGIOLOGICA

A Journal on Heart and Vascular Diseases


Official Journal of the Italian Society of Angiology and Vascular Pathology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,695


eTOC

 

  STENTS FOR CORONARY HEART DISEASE


Minerva Cardioangiologica 2011 February;59(1):31-8

Copyright © 2011 EDIZIONI MINERVA MEDICA

language: English

New drug-eluting stents with biodegradable polymers

Van Der Giessen W. J. 1, 2, Van Beusekom H. M. M. 1

1 Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands; 2 Interuniversity Cardiology, Institute of the Netherlands (ICIN-KNAW) Utrecht, The Netherlands


PDF  


Current drug-eluting stents (DES) perform well compared to bare metal stents. However, long-term rates of major adverse events and in particular repeat revascularization by PCI are still an issue. In this concise review we will discuss the possibilities of biodegradable coatings to improve biocompatibility of DES. Among the various members of the synthetic biodegradable polymer family, polyesters are widely used and attractive for their ease of degradation, with degradation products often being resorbed through general metabolic pathways. A new development is surface functionalization of polyesters to improve endothelialization.

top of page

Publication History

Cite this article as

Corresponding author e-mail

w.j.vandergiessen@erasmusmc.nl