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A Journal on Heart and Vascular Diseases

Official Journal of the Italian Society of Angiology and Vascular Pathology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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Minerva Cardioangiologica 2007 December;55(6):815-9


language: English

Vascular occlusion as a late complication of the Angio-Seal closure device. A review of literature

Van Den Broek T., Liqui Lung P. F., Suttorp M. J., Eefting F. D., Schipper M. E. I., Vink A.

1 Department of Surgery Rivierenland Hospital, Tiel, The Netherlands 2 Department of Pathology University Medical Centre Utrecht, Utrecht, The Netherlands 3 Department of Cardiology St. Antonius Hospital, Nieuwegein, The Netherlands


Although early vascular complications of the Angio-Seal closure device have been well described, little is known about late vascular complications due to this device. The aim of this paper is to discuss late femoral stenosis associated with the use of the Angio-Seal closure device. A literature search was performed using ‘Medline’, ‘Embase’ and ‘The Cochrane Library’ to identify relevant articles published up to the first of May 2007. Late occlusion was defined as an occlusion after approximately one week after Angio-Seal deployment. All together, eleven relevant papers were available. The reported prevalence of late vascular stenosis associated with Angio-Seal use varies between 1/961 and 4/175. Claudication was the most frequently reported complaint. In most cases, late stenosis due to the use of the Angio-Seal required surgery. Vascular obstruction due to the device has been reported up to 6 months after placement. In conclusion, vascular stenosis due to the use an Angio-Seal closure device is a complication that not only occurs in the first few days after placement, but also in the following months. In every patient developing complaints of arterial insufficiency after using an Angio-Seal, local arterial stenosis due to the device should be considered in the differential diagnosis. It therefore is important to register the use of the device in the patient chart.

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