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A Journal on Heart and Vascular Diseases
Official Journal of the Italian Society of Angiology and Vascular Pathology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,752
Minerva Cardioangiologica 2002 December;50(6):621-36
Interventional procedures in acute myocardial infarction
Kostur M. R. J., Degeare V. S.
Acute myocardial infarction (AMI) is a leading cause of death in the western world. Primary percutaneous intervention (PCI) has emerged as an effective therapy that may improve survival and decrease morbidity in patients with AMI. Our article discusses the advantages of PCI over thrombolytic therapy and reviews currently available techniques. Rescue angioplasty, adjunctive pharmacologic therapies, economic and feasibility considerations are also discussed. Emerging therapies are also addressed. Evidence supports the first-line use of PCI for AMI. Furthermore, primary PCI appears superior to thrombolytic therapy for AMI in many patient populations, especially the elderly, patients with prior coronary artery bypass surgery, patients with congestive heart failure and in patients with cardiogenic shock. Advancements in equipment and techniques and emerging adjunctive therapies will continue to enhance this therapy and improve its efficacy.