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MINERVA CARDIOANGIOLOGICA

A Journal on Heart and Vascular Diseases


Official Journal of the Italian Society of Angiology and Vascular Pathology
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Minerva Cardioangiologica 2001 October;49(5):307-16

language: English, Italian

What drug must be used to avoid the most common hypertensive complications?

Cacciapuoti F.


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After recalling that cardiovascular complications represent the most frequent cause of mortality and morbidity in hypertensive patients, the author describes the main mechanism responsible for increased plasma level concentrations of Angiotensin in this syndrome. He subsequently illustrates the effects of ACE-inhibitors, differentiating them from AT1-receptors. The anti-hypertensive actions of new b-blockers, like Carvedilol and Nebivolol are also explained. In addition, the anti brain hemorrhage and heart-failure effects of diuretics in hypertensive patients are briefly summarised. Finally, the anti-calcinotic effect and anti-embolic action of calcium-antagonist drugs are also underlined.

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