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MINERVA CARDIOANGIOLOGICA

A Journal on Heart and Vascular Diseases


Official Journal of the Italian Society of Angiology and Vascular Pathology
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Minerva Cardioangiologica 2001 June;49(3):197-210

language: Italian

Gastroesophageal Reflux Disease and chest pain

Pellicano R., Oliaro E., Berrutti M., Ponzetto A., Rizzetto M.


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Gastroesophageal reflux disease (GERD) is highly prevalent in the general population.
Heartburn and acid regurgitation are considered the ''typical'' presentation of GERD, that however might represent a major pathogenic mechanism in patients with chest pain without coronary artery disease. Chest pain in this instance is often successfully treated with high-dose antisecretory drugs, but the pathogenetic mechanism remains unclear. Further research is needed to clarify the role of GERD on the pathogenesis of chest pain and to ascertain whether a medical or surgical anti-secretory treatment could represent a possible approach.
Patients with non-cardiac chest pain of unknown origin should be carefully screened for the occurrence of GERD.

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