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A Journal on Heart and Vascular Diseases
Official Journal of the Italian Society of Angiology and Vascular Pathology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,752
Minerva Cardioangiologica 1999 April;47(4):127-36
Colon ischemia-reperfusion syndrome after abdominal aortic cross-clamping
Scorza R., Ghilardi G., Kunkl E.
Aortic cross-clamping is the cornerstone of abdominal aortic aneurysm surgery. The transient ischemia of the inferior hemisoma, and mainly of the large bowel, is then a current condition, usually well tolerated. At the time of vascular clamps removal, the ischemia-reperfusion syndrome may take place, and evolution toward multiple organ failure is an actual risk. The large bowel has a crucial role in the sequence of events causing ischemia-reperfusion syndrome, even when intestinal ischemia is not evident during aneurysmectomy.
In this paper, current concepts of ischemia-reperfusion syndrome are reviewed, and the role of the colon after abdominal aortic cross-clamping for aneurysmectomy is focused. Principles of prevention of MOF from ischemia-reperfusion syndrome are pointed out.