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Indexed/Abstracted in: EMBASE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,246
Online ISSN 1827-160X
Pellicano R. 1, Ponzetto A. 1, 2, Smedile A. 1, 2, Rizzetto M. 1, 2
1 Department of Gastro-Hepatology, Molinette Hospital, Turin, Italy;
2 Department of Internal Medicine, University of Turin, Turin, Italy
Helicobacter pylori (H. pylori) infection represents the major causal agent of several acute and chronic gastroduodenal diseases including peptic ulcer, gastric carcinoma, and mucosa-associated lymphoid tissue lymphoma. Moreover, this bacterium has been involved in many extragastric manifestations. As genomic techniques improve and become more readily available, researchers are able to solve some of the unexplained issues of H. pylori pathogenesis. To date it is possible to discover the function of hundreds of gene products and gain insight into posttranslational modification through proteomics. These consent to improve our understanding concerning its interaction with the host, genetic diversity and the mechanism underlying its evolution and adaptive potential.