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Home > Journals > Minerva Biotecnologica > Past Issues > Minerva Biotecnologica 1998 June;10(2) > Minerva Biotecnologica 1998 June;10(2):71-6



A Journal on Biotechnology and Molecular Biology

Indexed/Abstracted in: EMBASE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,246

Frequency: Quarterly

ISSN 1120-4826

Online ISSN 1827-160X


Minerva Biotecnologica 1998 June;10(2):71-6


The inter­re­la­tion of ­body ­growth ­with ­growth hor­mone, ­insulin-­like ­growth ­factor and pro­lactin ­levels in juve­nile ­tilapia (Ore­och­romis ­aureus)

Guillén I. 1, Estrada M. P. 1, Morales R. 1, Melamed P. 2, De La Fuente J. 1

1 Mam­malian ­Cell ­Genetics Divi­sion, ­Centro de ­Ingeniería ­Genética y ­Biotecnología, ­Havana, ­Cuba;
2 Tel ­Aviv Uni­ver­sity, Depart­ment of ­Zoology, Tel Aviv, ­Israel

­Serum ­growth hor­mone (GH), pro­lactin (PRL) con­cen­tra­tions and GH and ­insulin-­like ­growth ­factor (IGF) ­mRNA ­levels ­were fol­lowed in ­growing ­tilapia (O. ­aureus) ­from ­hatching to juve­nile ­stages ­under ­normal hus­bandry con­di­tions and ­under nat­ural con­di­tions of tem­per­a­ture and pho­to­pe­riod, ­water ­oxygen con­tent and ­water tem­per­a­ture. The incre­ment in ­body ­length and ­weight ­showed ­biphasic ­kinetics ­with a ­slow ­curve in the ­initial ­stages of ­growth (up to 10 g of ­weight) and an ele­va­tion in ­months 6-8 of ­life ­with an ­increase in the ­body ­weight ­from 10 to ­over 100 g. Cir­cu­lating ­serum GH and PRL ­levels and GH and IGF ­mRNA ­levels ­showed a pul­sa­tile pat­tern, con­sis­tent ­with the induc­tion of IGF syn­thesis by GH and the exis­tence of a neg­a­tive feed­back of IGF on GH expres­sion in ­tilapia. Fur­ther­more, low GH ­serum ­levels gen­er­ally cor­re­lated ­with a ­higher rel­a­tive con­di­tion ­factor of the ­fish. Our ­results sug­gest ­that low ­changing GH cir­cu­lating ­levels are suf­fi­cient to sus­tain ­growth in ­early ­stages of devel­op­ment in ­tilapia.

language: English


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