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A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care

Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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Minerva Anestesiologica 2016 Nov 23

language: English

Hypobaric versus isobaric spinal Levobupivacaine for total hip arthroplasty

Alessandro VERGARI 1, Luciano FRASSANITO 1, Roberta NESTORINI 1, Cosimo T. CAPUTO 1, Angelo CHIERICHINI 1, Enrico DI STASIO 2, Marco ROSSI 1

1 Istituto di Anestesia e Rianimazione, Polo Emergenza e Medicina Interna, Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy; 2 Istituto di Chimica Clinica, Polo Diagnostica per Immagini e Medicina di Laboratorio, Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy


BACKGROUND: Spinal anesthesia (SA) in the lateral decubitus position is often used to perform total hip arthroplasty (THA). Hypobaric local anesthetic ensures enhanced and prolonged sensory and motor block in the involved side. The aim of this study was to compare the intraoperative anesthetic efficacy of hypobaric with isobaric levobupivacaine solutions for THA.
METHODS: Forty patients scheduled to elective THA were allocated into two groups: isobaric levobupivacaine group (IL group) and hypobaric levobupivacaine group (HL group). All the patients were placed with the operative side uppermost on the surgical table and spinal anesthesia was performed with 4 ml (12,5 mg) of selected solution. The evolution of sensory and block on nondependent (operative) and dependent sides were checked.
RESULTS: Regarding the nondependent side the onset times for maximal sensory block level in the in HL group was 17,8 ± 1,1 min vs 24,2±4,1 min in IL group. In HL group the onset time for motor block was 9,2 + 3,5 min vs 15,6 + 5,4 min in IL group. The sensory regression time to L2 was significantly prolonged in HL group (192 ± 30,3 min vs 111 ± 13,4 min). After surgery in HL group the residual motor block degree was 2,4 ± 0,9, vs 0,2 ± 0,4 in IL group.
CONCLUSIONS: In patients undergoing THA under spinal anesthesia 12.5 mg of hypobaric levobupivacaine, compared with the same dose of isobaric levobupivacaine, allow shorter onset time for sensory block and delayed regression of sensory and motor block in the nondependent side.

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