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MINERVA ANESTESIOLOGICA

A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care


Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
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Minerva Anestesiologica 2017 April;83(4):402-11

DOI: 10.23736/S0375-9393.16.11608-6

Copyright © 2016 EDIZIONI MINERVA MEDICA

language: English

High flow oxygen therapy in adult critically ill patients

Lorenzo DEL SORBO 1, Alice VENDRAMIN 1, Sangeeta MEHTA 2

1 Interdepartmental Division of Critical Care Medicine, University Health Network, University of Toronto, Toronto, ON, Canada; 2 Department of Medicine, Mount Sinai Hospital, and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada


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High flow oxygen therapy is characterized for its ability to meet or exceed the high peak inspiratory flow of the patients with acute respiratory failure. Despite the lack of definitive evidence regarding its efficacy in improving clinically significant outcomes, its application has been rapidly spreading over the last decade. In this review we discuss the potential physiologic mechanisms of benefit as well as the most recent clinical trials investigating its role in adult critically ill patient.


KEY WORDS: Oxygen inhalation therapy - Respiratory insufficiency - Critical illness

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Publication History

Issue published online: April 12, 2017
Article first published online: December 1. 2016
Manuscript accepted: November 30, 2016
Manuscript revised: November 8, 2016
Manuscript received: July 26, 2016

Cite this article as

Del Sorbo L, Vendramin A, Mehta S. High flow oxygen therapy in adult critically ill patients. Minerva Anestesiol 2017;83:402-11. DOI: 10.23736/S0375-9393.16.11608-6

Corresponding author e-mail

lorenzo.delsorbo@utoronto.ca