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MINERVA ANESTESIOLOGICA

A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care


Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
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Minerva Anestesiologica 2015 December;81(12):1377-83

Copyright © 2015 EDIZIONI MINERVA MEDICA

language: English

Vasopressin in cirrhosis and sepsis: physiology and clinical implications

Wagener G. 1, Bakker J. 2, 3

1 Department of Anesthesiology, College of Physicians and Surgeons of Columbia University New York, New York, NY, USA;
2 Department of Intensive Care Adults, Erasmus MC University Medical Center, Rotterdam, The Netherlands;
3 Department of Pulmonology, Allergy and Critical Care, College of Physicians and Surgeons of Columbia University New York, New York, NY, USA


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Arginine-vasopressin (AVP) is an important hormone in the regulation of plasma osmolality and blood volume/pressure. In clinical practice it is frequently used in the treatment of septic shock and decompensated cirrhosis. In this review the physiology of AVP and its analogues is presented. In addition the use of AVP in cirrhosis and sepsis is reviewed.

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gw72@cumc.columbia.edu