Home > Journals > Minerva Anestesiologica > Past Issues > Minerva Anestesiologica 2015 September;81(9) > Minerva Anestesiologica 2015 September;81(9):1010-18

CURRENT ISSUE
 

ARTICLE TOOLS

Reprints

MINERVA ANESTESIOLOGICA

A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care


Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 2,623


eTOC

 

EXPERT OPINION  FREEfree


Minerva Anestesiologica 2015 September;81(9):1010-18

Copyright © 2015 EDIZIONI MINERVA MEDICA

language: English

Blood glucose amplitude variability in critically ill patients

Meyfroidt G.

Intensive Care Medicine, University Hospitals Leuven, Leuven, Belgium


FULL TEXT  


While the discussion on the optimal blood glucose (BG) level target in critically ill patients is on-going, attention shifts towards other aspects of the BG signal, such as hypoglycemia and blood glucose amplitude variability (BGAV). A large number of observational and mostly retrospective studies have demonstrated an association between increased BGAV and worse outcomes. This observed association could partially be explained by endogenous factors such as changes in the status of the patient that cannot be externally influenced. On the other hand, exogenous factors such as insulin and caloric infusions could play a role in increasing or decreasing BGAV. In this review article, intuitive concept of “variability” will be clarified, and possible metrics to quantify BGAV are discussed. Whether it is feasible to actively minimize BGAV in order to improve the outcome of critically ill patients, is questionable.

top of page

Publication History

Cite this article as

Corresponding author e-mail

geert.meyfroidt@uzleuven.be