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A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care

Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
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Minerva Anestesiologica 2011 November;77(11):1099-107

language: English

Pediatric delirium in the pediatric intensive care unit: a systematic review and an update on key issues and research questions

Creten C. 1, Van Der Zwaan S. 1, Blankespoor R. J. 1, Leroy P. L. J. M. 2, Schieveld J. N. M. 1

1 Division of Child and Adolescent Psychiatry and Psychology, Department of Psychiatry and Psychology, Maastricht University Medical Centre, European Graduate School of Neuroscience, Maastricht, The Netherlands;
2 Division of Pediatric Intensive Care, Department of Pediatrics, Maastricht University Medical Centre, European Graduate School of Neuroscience, Maastricht, The Netherlands


There was a dearth in awareness and knowledge regarding pediatric delirium (PD) at the pediatric intensive care unit (PICU). The aim of this study is to highlight the most recent and up-to-date findings of current literature -by means of a systematic review (SR) method-, and to present the key issues and research questions. A SR of the literature published between 24 March 2009 and 10 March 2011. Eight new articles were identified which included (literature) reviews, journal commentaries, and observational studies. There still is a dearth of literature on PD, with also a variable level of evidence (1b - 5), especially in relation to critical illness. To be able to further clarify PD in the PICU, additional research questions are provided for future research.

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