Advanced Search

Home > Journals > Minerva Anestesiologica > Past Issues > Minerva Anestesiologica 2004 December;70(12) > Minerva Anestesiologica 2004 December;70(12):809-21

ISSUES AND ARTICLES   MOST READ   eTOC

CURRENT ISSUEMINERVA ANESTESIOLOGICA

A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care

Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 2,036

Frequency: Monthly

ISSN 0375-9393

Online ISSN 1827-1596

 

Minerva Anestesiologica 2004 December;70(12):809-21

ANESTHESIA 

    ORIGINAL ARTICLES

High volume of subarachnoid levobupivacaine decreases drug requirement in first stage labor analgesia

Parpaglioni R. 1, Frigo M. G. 1, Sebastiani M. 1, Lemma A. 1, Barbati G. 2, Celleno D. 1

1 Anesthesia and Resuscitation Unit Fatebenefratelli General Hospital, Rome, Italy
2 AfaR - Center of Medical Statistics & IT Fatebenefratelli General Hospital, Rome, Italy

Aim. Using the statistic method of sequential allocation, we realized a prospective double-blind study in order to establish the minimum local anesthetic concentration (MLAC) of large intrathecal volume of levobupivacaine, during the first stage labour analgesia in spontaneous and induced labouring women.
Methods. Seventy-five nulliparous, at term, with cervical dilatation <5 cm parturients requesting combined spinal/epidural analgesia, were enrolled. The starting concentration was chosen according to recent literature. Total volume of study solution was 10 ml and efficacy was assessed with a visual analogue pain scal at the height of the uterine contraction.
Results. We established that MLAC of levobupivacaine, in 10 ml intrathecal volume, during the first stage of spontaneous and induced labour was 0.0134% and 0.0195%, respectively. No complications occurred during the study and the only side effect was shivering, which is common even in other anesthetic techniques. We produced a very selective sensitive block. Neither sympathetic nor motor block occurred.
Conclusion. Low intrathecally concentration of local anesthetic allows the anesthetist to reduce the total amount of drug and improves not only the differential blockade between motor and sensitive but also between sympathetic and sensitive fibers.

language: English, Italian


FULL TEXT  REPRINTS

top of page