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A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care
SEPSI SMART 2001
Minerva Anestesiologica 2001 April;67(4):307-9
Antibiotic therapy in Italy
Malacarne P., Rossi C.
Azienda Ospedaliera Pisana II Rianimazione
*Istituto di Ricerche Farmacologiche «M. Negri» Laboratorio di Epidemiologia Clinica
Data concerning antibiotic therapy in italian ICUs are presented. These data were not directly measured: they have been derived from a previous study on costs of intensive care treatments. 78% of 1065 patients received antibiotic therapy. Empirical therapy was started in 82% of septic patients. 93% of septic patints had at least one antibiogram. In 96% of cases, 2 or more antibiotics were given. 85% of surgical non septic patients received antibiotic prophylaxis for an average of 3.6 days, with a 3rd generation cephalosporine in the majority of cases. 60% of medical non septic patients rceived antibiotic prophylaxis for an average of 6.2 days, mostly with a 3rd generation cephalosporine. These data raise doubts about the proper use of prophlaxis. These data can be considered a useful starting point for the development of a program of surveillance of infections in Italian ICUs.