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Online ISSN 1827-1596
ACUTE RESPIRATORY FAILURE
From the Pulmonary-Critical Care Medicine Branch National Institutes of Health, Bethesda, USA
Mechanical ventilation is an important therapeutic technique for patients with respiratory failure. Nonetheless, it can be potentially dangerous ,worsening by itself pre-existing lesions and producing new ones. The author carefully reviews the results of a number of long term studies in large animals, which highlight the factors causing ventilator-induced lung injury.When the pathology is not manageable with non invasive approach, invasive mechanical ventilation should be tailored to the patient to avoid iatrogenic damage.