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CURRENT ISSUEMINERVA ANESTESIOLOGICA

A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care


Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
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ACUTE RESPIRATORY FAILURE  SMART 2001


Minerva Anestesiologica 2001 April;67(4):193-7

language: English

Genetic susceptibility to respiratory diseases

Villar J.

Research Insti­tute, Hos­pi­tal N. S. de Can­de­lar­ia Tene­rife, ­Canary ­Islands, ­Spain Asso­ciate Sci­en­tist, Depart­ment of Med­i­cine Mount ­Sinai Hos­pi­tal, Toron­to, Can­a­da
Clin­i­cal Pro­fes­sor, Crit­i­cal ­Care Med­i­cine, Mer­cer Uni­ver­sity, ­Macon, Geor­gia, USA


FULL TEXT  REPRINTS


As a result of the progress in molecular biology and genetics over the last 20 years, now it seems clear that the pathogenesis of most diseases is influenced by the genotype, the environment and the nature of the process which leads to the injury. Current evidence also suggests that genetic factors are associated with susceptibility to pulmonary diseases. The author reviews some of these complex interactions suggesting that even the inflammatory response during lung injury can be influenced by genetic polymorphisms.

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