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MINERVA ANESTESIOLOGICA

A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care


Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
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BRAIN FUNCTION MONITORING IN ANAESTHESIA  


Minerva Anestesiologica 2000 May;66(5):398-402

language: English

Bispectral index and anaesthesia in the elderly

Renna M., Venturi R.

From the Department of Anaesthesia Ealing Hospital, London (UK)



Background. Due to phar­ma­cok­i­net­ic and phar­ma­cod­y­nam­ic rea­sons, the eld­er­ly are at par­tic­u­lar ­risk of incur­ring unwant­ed ­side ­effects of ­drugs com­mon­ly ­used in anaesthe­sia. The bispec­tral ­index (BIS) is an EEG-­derived val­ue ­that meas­ures the sed­a­tive com­po­nent of the anaesthet­ic ­state. The BIS ­could be use­ful in guid­ing titra­tion of anaesthet­ic ­drugs in the eld­er­ly.
Methods. A ­review of the pub­lished ­data was per­formed by the ­authors in ­order to ­assess the suit­abil­ity of BIS tech­nol­o­gy appli­ca­tion to the ger­i­at­ric pop­u­la­tion.
Results. Age-relat­ed EEG dif­fer­enc­es ­exist in the nor­mal pop­u­la­tion but ­they do not ­affect the BIS. The BIS cor­re­lates ­with ­depth of seda­tion inde­pen­dent­ly of age. Senile demen­tia may be asso­ciat­ed ­with sig­nif­i­cant­ly low­er BIS val­ues.
Conclusions. The BIS is a use­ful guid­ance for titra­tion of anaesthet­ic ­drugs in the eld­er­ly. The pres­ence of ­senile demen­tia may be a con­found­ing fac­tor in the inter­pre­ta­tion of the BIS val­ues dur­ing anaesthe­sia.

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