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A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care
UPDATE IN ANAESTHESIA
Minerva Anestesiologica 2000 May;66(5):264-7
New Halogenated agents. Should I change my practice?
From the Department of Anaesthesia CHU Dupuytren - Limoges (France)
Sevoflurane and Desflurane are relatively new halogenated agents which make induction and control of depht of anaesthesia easier, recovery rapid and of good quality and they have less side-effects and toxicity. In children sevoflurane could replace halothane because it provides smooth and rapid induction with less cardiovascular depression and arythmias. Desflurane is not used because of its pungent odour. In adults sevoflurane could be preferred to desflurane because it allows rapid induction and laryngeal mask insertion or tracheal intubation without miorelaxants, a similar time of recovery, no clinical evidence for renal and hepatic toxicity, no more costs for anaesthesia for a lower MAC.