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A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care

Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
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Minerva Anestesiologica 1999 April;65(4):169-74


language: English

Propofol in the anaesthetic management of percutaneous rhizolysis for trigeminal neuralgia

Cafiero T. 1, Razzino S. 1, Mastronardi P. 2, Cappabiancha P. 3, Alfieri A. 3

1 Anesthesia and Resuscitation Service, San Rocco Hospital, ASL CE/2, Sessa Aurunca; 2 Department of Anesthesia and Resuscitation, University of Naples “Federico II”, Naples; 3 Department of Neurosurgery, University of Naples “Federico II”, Naples


Background. To eval­u­ate the effi­ca­cy of pro­pof­ol as the ­sole anaesthet­ic ­agent for the anaes­thet­ic man­age­ment of the tri­gem­i­nal rhi­zol­y­sis.
Methods. Experimental ­design: retrospective ­study. Setting: operating ­room of the Neuro-surgery Department at University. Patients: 200 ­patients ­were stud­ied, 115 ­males and 85 ­females, ­with ­mean age of 62.8±3.6 ­years, ASA stat­us I, II or III and ­with var­i­ous under­ly­ing med­i­cal prob­lems. Interventions: patients ­were pre­med­i­cat­ed ­with atro­pine 0.01 mg/kg iv 10 min ­before the induc­tion of anaesthe­sia. The induc­tion ­dose of P was titrat­ed to the ­desired lev­el in accord­ing to age and clin­i­cal con­di­tions. After induc­tion of anaesthe­sia the sur­geon start­ed the nee­dle place­ment ­through the fora­men ­ovale in the tri­gem­i­nal cis­tern. Measurements: during ­both pro­ce­dures the ­mean ­dose of P, induc­tion and recov­ery ­times, ­side ­effects and com­pli­ca­tions and qual­ity of anaesthe­sia ­were ­assessed. Statistical anal­y­sis of the ­data was car­ried out ­using ANO­VA for repeat­ed meas­ures and Bonferroni “t”-­test and a val­ue of p<0.05 was con­sid­ered to be sig­nif­i­cant.
Results. Anaesthesia was suc­cess­ful­ly ­induced ­after a ­mean ­dose of 1.9 mg/kg of P dur­ing PG and of 2.1 mg/kg dur­ing PR. A few ­side ­effects and ­short recov­ery ­time ­were record­ed in all cas­es. P ­also pro­vid­ed an ade­quate car­di­o­vas­cu­lar stabil­ity dur­ing PG and PR.
Conclusions. In con­clu­sion, P can be con­sid­ered suit­able for ­this par­tic­u­lar neu­ro­sur­gi­cal pro­ce­dure requir­ing ­short peri­od of anaesthe­sia and rap­id recov­ery ­time in ­order to com­mu­ni­cate ­with the neu­ro­sur­geon dur­ing the sen­so­ry test­ing.

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