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A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care
ORIGINAL ARTICLES ANESTHESIOLOGY
Minerva Anestesiologica 1999 April;65(4):169-74
Propofol in the anaesthetic management of percutaneous rhizolysis for trigeminal neuralgia
Cafiero T. 1, Razzino S. 1, Mastronardi P. 2, Cappabiancha P. 3, Alfieri A. 3
1 Anesthesia and Resuscitation Service, San Rocco Hospital, ASL CE/2, Sessa Aurunca;
2 Department of Anesthesia and Resuscitation, University of Naples “Federico II”, Naples;
3 Department of Neurosurgery, University of Naples “Federico II”, Naples
Background. To evaluate the efficacy of propofol as the sole anaesthetic agent for the anaesthetic management of the trigeminal rhizolysis.
Methods. Experimental design: retrospective study. Setting: operating room of the Neuro-surgery Department at University. Patients: 200 patients were studied, 115 males and 85 females, with mean age of 62.8±3.6 years, ASA status I, II or III and with various underlying medical problems. Interventions: patients were premedicated with atropine 0.01 mg/kg iv 10 min before the induction of anaesthesia. The induction dose of P was titrated to the desired level in according to age and clinical conditions. After induction of anaesthesia the surgeon started the needle placement through the foramen ovale in the trigeminal cistern. Measurements: during both procedures the mean dose of P, induction and recovery times, side effects and complications and quality of anaesthesia were assessed. Statistical analysis of the data was carried out using ANOVA for repeated measures and Bonferroni “t”-test and a value of p<0.05 was considered to be significant.
Results. Anaesthesia was successfully induced after a mean dose of 1.9 mg/kg of P during PG and of 2.1 mg/kg during PR. A few side effects and short recovery time were recorded in all cases. P also provided an adequate cardiovascular stability during PG and PR.
Conclusions. In conclusion, P can be considered suitable for this particular neurosurgical procedure requiring short period of anaesthesia and rapid recovery time in order to communicate with the neurosurgeon during the sensory testing.