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A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care

Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 2,036

Frequency: Monthly

ISSN 0375-9393

Online ISSN 1827-1596


Minerva Anestesiologica 1998 June;64(6):267-70



Neuroleptanalgesia in patients undergoing percutaneous ultrasound-directed radiofrequency for primitive or secondary, single or multiple neoplastic lesions of the liver

Crespi G. 1, Ruffa D. 1, Farioli S. 1, Centemeri M. D. 1, Servadio G. 1, Foglia E. 1, Chiarello E. 1, Solbiati L. 2, Ierace T. 2, Dellanoce M. 2

1 ASL N. 3 - Busto Arsizio (Varese), U O Anestesia e Rianimazione;
2 ASL N. 3 - Busto Arsizio (Varese), U O Radiologia

Background. The use of percutaneous ultrasound-directed radiofrequency is a recent technique in non-surgical therapy of some neoplastic liver lesions. Purpose of this study is do demonstrate that the use of a narcosis-free analgesia allows to perform this procedure, which is generally painful and badly by the patient.
Methods. We treated 51 patients for a total of 126 procedures; the first 17 patients underwent a mono- or multipolar technique with uncooled electrodes, while the remaining 34 patients have been treated with double perfusion lumen electrodes with the chance of tipcooling. We used diidrobenzoperydol and fentanyl with a mean dose for each session of 209 μg for the first 17 patients and 109 μg for the other 34.
Results. Using VAS, we obtained a painless procedure in 42 patients and mild-pain sensations in 9 patients, while one hour after the procedure painless or light-pain sensation were observed in 49 patients and mild-pain in 2 patients, which required the use of FANS i.v. At discharge, all patients were pain-free or with very light pain sensation. We reduced the intra-hospital observation of patients from 5 to 3 hours, once the technique has been modified. 4 patients complained about nausea and 1 of these emesis. We did not ob-serve any cardiovascular, respiratory and/or neurological complications.
Conclusions. The use of neuroleptanalgesia allowed us to perform the described procedure with a good feeling by the patients.

language: Italian


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