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A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care
SAH-PATIENTS OUTCOME, COMPLICATIONS AND PREVENTION, FUTURE PROSPECTS PROCEEDINGS OF THE VIDEOCONFERENCE - October 5, 1996
SUBARACHNOID HEMORRHAGE: A MULTIDISCIPLINARY APPROACH - II
Minerva Anestesiologica 1998 May;64(5):257-9
Future prospects of pharmachological SAH treatment
Carteri A., Billeci D., Copetti E.
Ospedale Regionale «Ca’ Foncello» - Treviso, Divisione Clinicizzata di Neurochirurgia
The aim of pharmacological therapy in sub-arachnoid haemorrhage (SAH) is to prevent cerebral ischemia and consequent events. Vasospasm, energy decrease, alterated Ca++ homeostasis, lactic acidosis and free radicals are responsibles for cerebral ischemic damage. Drug therapy in SAH is necessary before, during and after surgical treatment. Nimodipine is the only drug used today and supported by many clinical trials; scientific trials, on using known and new substances in SAH drug therapy, are in progress.