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MEDICINA DELLO SPORT
A Journal on Sports Medicine
Official Journal of the Italian Sports Medicine Federation
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,163
Medicina dello Sport 2008 March;61(1):57-64
language: English, Italian
Family history of type 2 diabetes and altered maximal aerobic capacity in elite young athletes: a cross-sectional study
Pomara F. 1, Russo G. 2, Veca M. 2, Gravante G. 2
1 MedeorPoliambulatory, Palermo, Italy
2 Human Physiology Department of Experimental Medicine, Motor Science Faculty, University of Palermo, Palermo, Italy
Aim. Family history of type 2 diabetes is a predictive risk factor of illness in sedentary subjects and induces early phenotypic and metabolic alterations. The aim of this study was to determine whether a family history of diabetes in young male athletes had an effect on metabolic functional parameters.
Methods. The study population was 42 young male athletes with or without a family history of type 2 diabetes. Anthropometric parameters, body composition, and maximal aerobic capacity (V.O2max) were assessed.
Results. V.O2max was lower in the 13 athletes with a family history of diabetes (FH+) than in the 29 athletes without a family history of the disorder (FH–) matched for kilogram of body weight and fat-free mass (P <0.05, respectively). The mean increase in V.O2max was lower in the FH+ athletes than in that of the FH– athletes (15% vs 28%), compared to respective theoretical values.
Conclusion. Family history of type 2 diabetes can limit the positive metabolic adjustments induced by physical activity and should be considered a risk factor in prevention interventions.