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Official Journal of the Italian Sports Medicine Federation
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,163
Online ISSN 1827-1863
Pérez-Ruiz M. 1, Lucia A. 1, Vaquero A. F. 1, Banderas F. 2, Chicharro J. L. 3
1 Department of Morphology and Physiology, European University of Madrid, Spain;
2 Department of Toxicology and Forensic Medicine, Complutense University, Madrid, Spain;
3 Infirmary School, Faculty of Medicine, Complutense University, Madrid, Spain
Objective. The etiology of the changes in urine composition induced by intense and prolonged exercise is not well understood. The purpose of this investigation was to evaluate the incidence of hematuria, proteinuria and sediment alterations before, immediately after and during the 72 h following an endurance type of competition.
Experimental design. Fifty three athletes [28 long distance runners (R), 11 footballers (F), and 14 amateur cyclists (C)] formed the study population. Urine samples were taken before and 30 minutes, 6, 24, 48 and 72 hours after corresponding competitions to estimate changes in composition. Venous blood and urine samples obtained from 29 of the subjects (15 R and 14 C) served e determine creatinine clearance (glomerular filtrate index). Urine samples showing post-exercise proteinuria above reference values were further subjected immunochemical analysis of the proteins.
Results. Post-exercise hematuria was found in 60%, 28.57%, and 45.45% of R, C and F respectively although there was no significant difference between groups. Only 5 runners (33.3%) and 4 cyclists (28.57%) showed significant proteinuria (p<0.05) with albumin as the predominant protein. Mean post-exercise creatinine clearance [127.33±23.8 ml·(min-1·1.73 m2)-1] was significantly greater than the pre-exercise value but within physiological limits.
Conclusions. Exercise seems to induce reversible changes in urine composition with normal parameter values attained after 24 hours. No significant difference was found with respect to these cbanges between athlete groups.