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A Journal on Angiology
Official Journal of the , the International Union of Phlebology and the
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899
International Angiology 2016 Apr 15
Hybrid procedures for the lower limb chronic ischemia: what determines the outcome?
Konstantinos SPANOS 1, Georgios A. ANTONIOU 2, Vasileios SALEPTSIS 1, Athanasios ATHANASOULAS 1, Aikaterini DRAKOU 1, Stylianos KOUTSIAS 1, Athanasios D. GIANNOUKAS 1 ✉
1 Department of Vascular Surgery, University Hospital of Larisa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece; 2 Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK
BACKGROUND: To report the long term outcome of hybrid (combined open and endovascular) procedures for the management of multisegmental chronic peripheral arterial disease.
METHODS: A retrospective analysis from a single center during the period 2009- 2013. Patency rates, survival and limb salvage were the primary outcomes. Univariate and multivariate analyses were used to assess the association with various factors.
RESULTS: A total of 132 patients (116 males) with mean age of 69±1.4 years, were treated. The technical and hemodynamic success rates were 94% and 97.7% respectively. The primary and assisted primary patency rates in 36 months were 69.7% and 94.7%, respectively. The Hazard Ratio for primary and assisted primary patency failure was 1.94 (95% C.I. 1.07 - 3.51, p=0.029) and 5.55 (95% C.I. 1.15 - 26.79, p=0.033) times higher in diabetic patients, respectively. Limb salvage rate in 36 months was 87.9%. Rutherford category (p=0.046) and previous ipsilateral reconstruction (p=0.011) were the only factors associated with limb loss.
CONCLUSIONS: Hybrid procedures are associated with good long term outcomes in the treatment of multisegmental chronic peripheral arterial disease. Diabetes mellitus remains a determinant of worse outcome, while the severity of the disease and previous ipsilateral revascularization are associated with poorer limb salvage.