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A Journal on Angiology

Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899

Frequency: Bi-Monthly

ISSN 0392-9590

Online ISSN 1827-1839


International Angiology 2015 Nov 17

Catheter-directed thrombolysis combined with manual aspiration thrombectomy for acute inferior vena cava filter thrombosis

Li W.-D., Li C.-L., Qian A.-M., Zhang Y.-Q., Li X.-Q.

Department of Vascular Surgery, the Second Affiliated Hospital of Soochow University, Suzhou, 215000, China

AIMS: The occurrence of inferior vena cava (IVC) filter thrombosis has been reported, however, the optimal treatment of IVC thrombosis has not been established yet. The aim of this study was to assess the results of catheter-directed thrombolysis(CDT) combined with aspiration thrombectomy(AT) in the treatment for IVC filter thrombosis.
METHODS:A total of 35consecutive patients received endovascular treatment with CDT alone or CDT with AT for IVC filter thrombosis at second affiliated hospital of Soochow University from May 2009 to May 2014 were included in this study. The procedure, complications and clinical outcome between these two group were retrospectively reviewed.
RESULTS: The mean age of patients was 44.7±15.8 years (range: 17-74 years).The patients were consisted of 21 males and 14 females. CDT alone and CDT with AT were performed in 16 and 19 patients, respectively. The mean procedural time of CDT alone group was longer than CDT with AT group (99.5±51.4 h vs 64.9±35.9 h, p<0.05) and dose of urokinase used during the procedure was significantly decreased in CDT with AT group (2.1±1.1million IU vs 1.5±0.6 million IU, p<0.05). Besides, total number of complications in CDT with AT group was smaller than in CDT alone group(9 cases vs 4 cases, P<0.05).
CONCLUSIONS: Our results confirmed that CDT with AT was a safe and effective method in the treatment of acute IVC filter thrombosis. Compared with CDT alone, it was more excellent for less thrombolysis time and urokinase dose. In addition, it may decrease the occurrence of complications.

language: English


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