Home > Journals > International Angiology > Past Issues > International Angiology 2012 February;31(1) > International Angiology 2012 February;31(1):28-32

CURRENT ISSUE
 

ARTICLE TOOLS

Reprints

INTERNATIONAL ANGIOLOGY

A Journal on Angiology


Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,37


eTOC

 

ORIGINAL ARTICLES  


International Angiology 2012 February;31(1):28-32

Copyright © 2012 EDIZIONI MINERVA MEDICA

language: English

Impact of carotid artery stenting on plasma interleukin-6, tumor necrosis factor-α and C-reactive protein

Xia Z. Y. 1, Yang H. 2, Qu H. Q. 1, Cheng W. D. 1, Wang L. X. 3

1 Department of Neurology, Liaocheng People’s Hospital and Liaocheng Clinical School of Taishan Medical University Liaocheng, Shandong Province 252000, PR China; 2 Department of Neurology, The Third People’s Hospital of Liaocheng,Liaocheng, Shandong Province, 252000, PR China; 3 School of Biomedical Sciences,Charles Sturt University, Wagga Wagga, NSW 2678, Australia


PDF  


AIM:This study aimed to investigate the impact of carotid artery stenting (CAS) on plasma levels of interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α) and C-reactive protein (CRP).
METHODS: The levels of CRP, IL-6, and TNF-α were measured in 61 patients before CAS, 1 h, 2 weeks, 1 month, 6 months, and 12 months after the stenting.
RESULTS: The levels of CRP, IL-6 and TNF-α increased immediately after CAS (P<0.05 or <0.01). The levels of CRP, IL-6 and TNF-α in patients receiving two stents for multiple lesions or single diffusive lesions was also high than in patients receiving one stent for a single lesion (P<0.05 or <0.01). The levels of CRP, IL-6 and TNF-α in patients with restenosis (14/61, or 23%) were higher than in those without restenosis (P<0.05 or <0.01).
CONCLUSION: CAS was associated with a significant increase in plasma CRP, IL-6 and TNF-α. The levels of these inflammatory factors in patients with post-CAS restenosis were higher than in those without restenosis.

top of page

Publication History

Cite this article as

Corresponding author e-mail

lwang@csu.edu.au