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A Journal on Angiology

Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899

Frequency: Bi-Monthly

ISSN 0392-9590

Online ISSN 1827-1839


International Angiology 2008 December;27(6):500-6

    Original articles

Cost benefit of intermittent pneumatic compression for venous thromboembolism prophylaxis in general surgery

Nicolaides A. 1,2,3, Goldhaber S. Z. 4, Maxwell G. L. 5, Labropoulos N. 6, Clarke-Pearson D. L. 7, Tyllis T. H. 3, Griffin M. B. 8

1 Department of Vascular Surgery, Imperial College, London, UK
2 Department of Biological Sciences, University of Cyprus, Nicosia Cyprus
3 Vascular Screening and Diagnostic Centre, Nicosia, Cyprus
4 Cardiovascular Division, Brigham and Women’s Hospital, Boston, MA, USA
5 Division of Gynecologic Oncology, Walter Reed Army Medical Center, Washington, DC, USA
6 Department of Vascular Surgery and Vascular Laboratory, University of Medicine and Dentistry of New Jersey, NJ, USA
7 Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, NC, USA
8 Vascular Screening and Diagnostic Centre, London, UK

Aim. In moderate to high-risk general surgical patients, the cost effectiveness of mechanical prophylaxis for venous thromboembolism (VTE) is uncertain. Therefore, we determined the costs and savings of intermittent pneumatic compression (IPC) plus graduated compression stockings (GCS).
Methods. Postoperative VTE events in the absence of prophylaxis, efficacy of prophylaxis and costs of prophylaxis have been obtained from the English literature and Medicare 2004 reimbursement schedule.
Results. In 1000 moderate to high risk general surgical patients, in the absence of prophylaxis, the cost of investigating and treating 72 patients with clinical suspicion of DVT and 32 with PE is calculated to be $ 263 779. This corresponds to a cost of $ 263 per surgical patient. The cost of IPC combined with TED stockings in 1 000 similar patients would be $ 66 760, and the cost of diagnosis and treatment of the reduced numbers (69% reduction) of clinical VTE is $ 83 574 making a total of $ 150 344. This means a saving of $ 133 435 ($ 263 779-$ 150 344) per 1 000 patients. This corresponds to a saving of $ 113 per surgical patient. Sensitivity analysis demonstrates that despite variation in costs or efficacy for IPC plus GCS, marked savings persist.
Conclusion. Prophylaxis with IPC not only prevents VTE but also saves money.

language: English


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