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Official Journal of the , the International Union of Phlebology and the
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899
Online ISSN 1827-1839
Engellau L. 1, Albrechtsson U. 1, Höjgård S. 2, Norgren L. 3, Larsson E-M. 1
1 Department of Radiology, Lund University Hospital, Lund, Sweden
2 Department of Community Medicine and Lund University Centre for Health Economics (LUCHE), Lund University, Lund, Sweden
3 Department of Vascular Diseases, Lund University, Malmö University Hospital, Malmö, Sweden
Aim. Endovascular repair of abdominal aortic aneurysms (AAA) necessitates a long-term follow-up. These patients are often old and renal insufficiency is not unusual. Cost-effectiveness needs to be addressed in evaluating methods of follow-up. The aim of this study was to compare costs of 5 years follow-up with magnetic resonance imaging with contrast enhanced three-dimensional magnetic resonance angiography (MRI/MRA) with follow-up using CT with DSA, or CTA. We also assessed the impact of contrast media induced (CMI) nephropathy on follow-up costs.
Methods. We have implemented Swedish costs of CT with DSA, and CTA on the reported follow-up examinations from the EUROSTAR progress report 2000. The costs of follow-up with CT with DSA, or CTA were compared to a follow-up protocol with MRI/MRA. A cost analysis including a risk analysis of CMI nephropathy was made between MRI/MRA and CT with DSA, or CTA.
Results. Excluding the risk of CMI nephropathy, the 5 years follow-up cost in Euro (€) with MRI/MRA (€ 5715) is substantially higher than CT with DSA (€ 3 095) or CTA (€ 3573). The cost analysis favours MRI/MRA if the risk of CMI nephropathy from CT with DSA, or CTA is more than 5%.
Conclusion. MRI/MRA can be cost-effective for follow-up of endovascularly repaired AAA depending on the risk of CMI nephropathy for CT with DSA, and CTA. MRI/MRA should be the method of choice for patients with pre-existing renal insufficiency.