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Official Journal of the , the International Union of Phlebology and the
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899
Online ISSN 1827-1839
Symeonidis G., Papanas N., Giannakis I. *, Mavridis G., Lakasas G., Kyriakidis G., Artopoulos I. *
Second Department of Internal Medicine, “O Agios Dimitrios” Hospital, Thessaloniki, Greece
* Radiology Department, “O Agios Dimitrios” Hospital, Thessaloniki, Greece
Background. The aim of the present study was to evaluate the gravity of aortic arch calcification in adult Greek patients.
Methods. A total of 1027 patients (498 men, 529 women) were included. Aortic arch calcification was assessed by means of posteroanterior chest X-rays. These were stu-died by two radiologists blinded to the patients’ medical records. Calcification was graded as follows: grade 0 (no visible calcification), grade 1 (small spots of calcification or single thin calcification of the aortic knob), grade 2 (one or more areas of thick calcification), grade 3 (circular calcification of the aortic knob). All patients were clinically and electrocardiographically examined for coronary artery disease. The other parameters included in the analysis were age, sex, smoking, body-mass index, hypertension, dyslipidemia, diabetes mellitus and history of stroke.
Results. Calcification gravity was grade 0 in 421 patients (41%), grade 1 in 308 patients (30%), grade 2 in 216 patients (21%) and grade 3 in 82 patients (8%). In simple regression analysis the gravity of aortic arch calcification was positively correlated with age (p=0.01), diabetes mellitus (p=0.014), hypertension (p=0.022), dyslipidemia (p=0.038) and coronary artery disease (p=0.041). In multiple regression analysis it was associated with age (p=0.019), diabetes mellitus (p=0.02) and hypertension (p=0.03).
Conclusions. Gravity of aortic arch calcification in adult Greek patients may easily be assessed on routine chest X-rays and is positively correlated with coronary artery disease, as well as important cardiovascular risk factors (age, diabetes mellitus, hypertension and dyslipidemia).