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A Journal on Angiology

Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899

Frequency: Bi-Monthly

ISSN 0392-9590

Online ISSN 1827-1839


International Angiology 2002 September;21(3):233-6


Gravity of aortic arch calcification as evaluated in adult Greek patients

Symeonidis G., Papanas N., Giannakis I. *, Mavridis G., Lakasas G., Kyriakidis G., Artopoulos I. *

Second Department of Internal Medicine, “O Agios Dimitrios” Hospital, Thessaloniki, Greece
* Radiology Department, “O Agios Dimitrios” Hospital, Thessaloniki, Greece

Background. The aim of the ­present study was to evaluate the grav­ity of aor­tic arch cal­cifi­ca­tion in adult Greek ­patients.
Methods. A total of 1027 ­patients (498 men, 529 women) were includ­ed. Aortic arch cal­cifi­ca­tion was ­assessed by means of pos­te­roan­ter­i­or chest X-rays. These were stu-d­ied by two radiol­o­gists blind­ed to the ­patients’ med­i­cal ­records. Calcification was grad­ed as fol­lows: grade 0 (no vis­ible cal­cifi­ca­tion), grade 1 (small spots of cal­cifi­ca­tion or sin­gle thin cal­cifi­ca­tion of the aor­tic knob), grade 2 (one or more areas of thick cal­cifi­ca­tion), grade 3 (cir­cu­lar cal­cifi­ca­tion of the aor­tic knob). All ­patients were clin­i­cal­ly and elec­tro­car­di­o­graph­i­cal­ly exam­ined for cor­o­nary ­artery dis­ease. The other param­e­ters includ­ed in the anal­y­sis were age, sex, smok­ing, body-mass index, hyper­ten­sion, dys­lip­i­de­mia, dia­betes mel­lit­us and his­to­ry of ­stroke.
Results. Calcification grav­ity was grade 0 in 421 ­patients (41%), grade 1 in 308 ­patients (30%), grade 2 in 216 ­patients (21%) and grade 3 in 82 ­patients (8%). In sim­ple regres­sion anal­y­sis the grav­ity of aor­tic arch cal­cifi­ca­tion was pos­i­tive­ly cor­re­lat­ed with age (p=0.01), dia­betes mel­lit­us (p=0.014), hyper­ten­sion (p=0.022), dys­lip­i­de­mia (p=0.038) and cor­o­nary ­artery dis­ease (p=0.041). In mul­ti­ple regres­sion anal­y­sis it was asso­ciat­ed with age (p=0.019), dia­betes mel­lit­us (p=0.02) and hyper­ten­sion (p=0.03).
Conclusions. Gravity of aor­tic arch cal­cifi­ca­tion in adult Greek ­patients may eas­i­ly be ­assessed on rou­tine chest X-rays and is pos­i­tive­ly cor­re­lat­ed with cor­o­nary ­artery dis­ease, as well as impor­tant car­di­o­vas­cu­lar risk fac­tors (age, dia­betes mel­lit­us, hyper­ten­sion and dys­lip­i­de­mia).

language: English


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