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Official Journal of the , the International Union of Phlebology and the
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899
Online ISSN 1827-1839
Kudo F. A., Nishibe T., Miyazaki K., Flores J., Yasuda K.
Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Hokkaido, Japan
Background. The purpose of this study was to investigate the postoperative inflammatory reactions to albumin-coated Dacron grafts (ACGs), which are used in the repair of abdominal aortic aneurysm (AAA).
Methods. Experimental design: a retrospective study with a follow-up period of 14 days. Setting: University hospital. Patients: 50 patients admitted for elective AAA repair from January 1997 to January 2000. Interventions: each patient underwent AAA repair with an ACG (Bard, albumin-coated Dacron graft). Measures: the white blood cell (WBC) count, plasma C-reactive protein (CRP) concentration, and body temperature (BT) were determined. The preoperative data, the highest values of the postoperative data, and the values 2 weeks postsurgery were analyzed.
Results. The BT, CRP, and WBC increased and peaked at the 1st week postsurgery and then decreased gradually. The BT and WBC levels returned to normal within 2 weeks. The CRP level continued to show slightly elevated values in the 2nd week, but it was not significantly different compared to the preoperative data.
Conclusions. The use of an albumin-impregnated prosthesis for the reconstruction of AAA is biocompatible, since no significant increases in inflammatory reactions are observed in the 2nd week postsurgery.