Home > Journals > International Angiology > Past Issues > International Angiology 2001 June;20(2) > International Angiology 2001 June;20(2):110-7





A Journal on Angiology

Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899




International Angiology 2001 June;20(2):110-7

language: English

Brain CT infarction in patients with carotid atheroma. Does it pre­dict a ­future event?

Tegos T. J., Kalodiki E., Nicolaides A. N., Sabetai M. M., Stevens J. M. *, Thomas D. J. **

From the ­Irvine Labor­a­to­ry for Car­di­o­vas­cu­lar Invest­i­ga­tion and ­Research, Depart­ment of Vas­cu­lar Sur­gery
* Depart­ment of Radiol­o­gy, ** Depart­ment of Neu­rol­o­gy, Impe­ri­al Col­lege of Sci­ence, Tech­nol­o­gy and Med­i­cine, Lon­don, UK


Back­ground. The aim of the ­present study was to inves­ti­gate the pre­dic­tive value for sub­se­quent ­stroke of dif­fer­ent pat­terns of brain CT ­infarction in ­patients with carot­id ather­o­ma.
Meth­ods. Pros­pec­tive study on 138 ­patients, with 138 carot­id ­plaques, hav­ing, on pres­en­ta­tion, a great­er than 50% sten­o­sis on ­duplex scan­ning and asso­ciat­ed with an ipsi­lat­er­al (to the ­plaque) amau­ro­sis fugax (AF), hem­i­spher­ic tran­sient ischaem­ic ­attack (HTIA) or which were asymp­to­mat­ic. This carot­id ­artery ­defined the side of inter­est. All ­patients had a brain CT scan on pres­en­ta­tion and sub­se­quent­ly were fol­lowed for a peri­od of 1-5 years (mean 3.14). The base­line CT neu­ro­vas­cu­lar find­ings on the side of inter­est were clas­si­fied as pat­tern A (dis­crete sub­cor­ti­cal and cor­ti­cal ­infarctions), pat­tern B (hae­mod­y­nam­ic ­infarctions, widespread white mat­ter ­lesions, basal gan­glia ­infarctions and lacu­nae) and nor­mal CT.
­Results. On fol­low-up, 5/27 (18.5%) of ­patients with pat­tern A, 4/38 (10.5%) with pat­tern B and 3/73 (4.1%) with nor­mal CT appear­ance devel­oped ­stroke in the hem­i­sphere of inter­est (Cox regres­sion: p=0.02).
Con­clu­sions. Pat­tern A con­fers an unfa­vour­able prog­no­sis in ­patients with carot­id ather­o­ma who are ­either asymp­to­mat­ic or pre­sent­ed with amau­ro­sis fugax or hem­i­spher­ic tran­sient ischaem­ic ­attacks.

top of page

Publication History

Cite this article as

Corresponding author e-mail