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A Journal on Angiology

Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899

Frequency: Bi-Monthly

ISSN 0392-9590

Online ISSN 1827-1839


International Angiology 1998 June;17(2):93-6


Prevention of deep vein throm­bo­sis in knee arthro­plas­ty. Preliminary ­results from a ran­dom­ized con­trolled study of low molec­u­lar ­weight hep­ar­in vs foot pump com­pres­sion

Norgren L. *, Toksvig-Larsen S., Magyar G., Lindstrand A., Albrechtsson U.

From the Departments of Orthopedic Surgery and Diagnostic Radiology and Section of Vascular Surgery, Department of Surgery * - Lund University, Sweden

Background. We eval­u­at­ed in a ran­dom­ized con­trolled study the pos­sibil­ity to use foot pump mechan­i­cal com­pres­sion com­pared to rou­tine LMWH as pro­phy­lax­is ­against deep vein throm­bo­sis dur­ing knee arthro­plas­ty.
Methods. Forty ­patients were includ­ed in this pre­lim­i­nary ­report. Eleven ­patients with­drew, usu­al­ly dur­ing the early phase of the study.
Results. Among the 29 ­patients com­plet­ing a venog­ra­phy, 27% in the com­pres­sion group and none in the LMWH group had a DVT. This dif­fer­ence was sta­tis­ti­cal­ly sig­nif­i­cant (p<0.05). One fur­ther ­patient in the com­pres­sion group died from pul­mo­nary embo­lism 17 days post­op­er­a­tive­ly.
Conclusions. With the ­present study pro­to­col, mechan­i­cal foot pump com­pres­sion ­failed to be as effi­cient as LMWH pro­phy­lax­is.

language: English


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