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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE

A Journal on Internal Medicine and Pharmacology


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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2016 May;175(5):223-30

language: Italian

Le analisi di genere nei trials clinici: puro esercizio di stile o necessità clinica?

Giovanni PACINI, Gilberto BELLIA, Emanuela ZAGNI, Delia COLOMBO

Novartis Farma S.p.A., Origgio, Varese, Italia


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There is an ever increasing demand from physician, patients and associations for personalized targeted drugs. This demand is due to the fact that we still do not have a satisfactory level of patient-specific treatment in every pathologies. In order to meet this demand it is fundamental that more focus is put on gender differences and we recognize genetic gender diversity in the human species since reactions to drugs and outcomes of drug-treatment vary according to gender. Gender medicine is at the pioneering stage and for now is still not fully-explored. The aim of gender-medicine is to bring about an improvement in the treatment of various pathologies. This improvement need to take into account physio-pathological gender differences starting from base research and up to the patient bed-side.

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