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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2015 September;174(9):427-30
Acute hemolysis in glucose-6-phosphate dehydrogenase deficiency after coronary angiography
Küçükseymen S., Çağirci G., Köklü E., Yüksel I. O., Bayar N., Esin M., Arslan Ş.
Cardiology clinic, Antalya Training and Research Hospital, Antalya, Turkey
The contrast agents in current use are generally safe, however have some side reactions, can range from minor to severe, sometimes resulting in death. Nowadays, glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is known as one of the most common hereditary disorders of erythrocytes, causing intravascular hemolysis. Most of patients with G-6-PD deficient are usually asymptomatic, on the other hand can present by hemolytic anemia particularly after the administration of some drugs, exposure to fava beans, infections and during diabetic acidosis. We describe here a 44-year-old man with G-6-PD deficient, who developed acute severe hemolysis after diagnostic coronary angiography.