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Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1812
Lee J. K. 1, 2, Jung D. K. 1, Kim H. 3, Kim H. N. 4, Park Y. H. 5, Kang B. Y. 6
1 Department of Leisure and Sports, Sahmyook University, Seoul, Korea;
2 Fitness and Medicine Research Institute, Sahmyook University, Seoul, Korea;
3 Department of Health Promotion and Exercise, Daegu University, Kyungsan‑City, Korea;
4 School of Continuing Education, Daejin University, Gyunggi‑do, Korea;
5 College of Sport Science, Sungkyunkwan University, Gyeonggi‑do, Korea;
6 Department of Physical Education, Hanyang University, Seoul, Korea
AIM: The purpose of this study was to investigate the influences of the uVNTR polymorphism in the monoamine oxidase A (MAOA) gene on physiological and psychological factors of male kumdo players.
METHODS: A total of 66 kumdo players were recruited for this study, and divided into non-elite and elite players. Total genomic DNA was isolated from peripheral blood of participants, and the uVNTR polymorphism in the MAOA gene was analyzed using a PCR-direct detection method.
RESULTS: When two groups of kumdo players were compared, the mean values of left grip for elite kumdo players (44.2±7.5 kg) were significantly higher those of non-elite players (39.3±7.2 kg) (P<0.05). In addition, the uVNTR polymorphism in the MAOA gene may contribute to the inter-individual difference of blood lipoprotein(a) (Lp(a)) level in kumdo players (P<0.05). In particular, blood Lp(a) level of participants with the 4R allele (11.2±11.7 mg/dL) was significantly higher compared to those with the 3R allele (6.6±6.3 mg/dL).
CONCLUSION: Data from our study suggest that the uVNTR polymorphism in the MAOA gene may be a useful genetic marker influencing the inter-individual difference of blood Lp(a) level of kumdo players. Conduct of further studies using a larger sample size will be required in order to clarify the precise mechanism behind this association.