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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2014 April;173(4):207-12
Flowmetry of uterine arteries and pre-eclampsia
Zarbo G., Giannone T. T., Giunta M. R., Carbonaro A., Pafumi C., Palumbo M. A.
Istituto Di Patologia Ostetrica e Ginecologica, Azienda Ospedaliera Universitaria, Policlinico-Vittorio Emanuele, Catania, Italia
Today preeclampsia is responsible for 10-15% of maternal deaths during pregnancy. In the past it was considered pregnancy limited disease that can be resolved with fetal death or birth, today, however, many studies have shown that maternal vasculopathy, typical of the disease can last for years after the onset of preeclampsia. In view of the difficulties that are often encountered in the therapeutic treatment of this disease, the identification of a biochemical test or biophysical able to indicate the possibility of developing pre-eclampsia in pregnant women is a particularly important objective in research. Our study aims to evaluate the onset of preeclampsia and predictive markers metric flows in the uterine arteries. It was conducted on 21 women who had risk factors for the onset of the disease, by performing at 24-25 weeks of gestation flowmetry of the uterine arteries to evaluate the resistance index (RI) and the presence of proto diastolic notch (notch). Our results confirm that an average value of RI >0.60 and/or the presence of notch at the 24 week of gestation could be used as an index of predictivity of preeclampsia.