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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE

A Journal on Internal Medicine and Pharmacology


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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2013 April;172(4):303-8

language: English, Italian

Cribriform adenocarcinoma of the tongue

Mevio E. 1, Mullace M. 1, Viglione S. 1, Cazzaniga M. 2, Migliorini L. 2

1 Department of Otorhinolaryngology, Fornaroli Hospital, Magenta, Italy;
2 Department of Pathology, Fornaroli Hospital, Magenta, Italy


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The cribriform adenocarcinoma of the tongue (CAT) was identified as a rare specific entity, characterized by typical histological pattern and localization to the tongue, by Michal in 1999. Recently, identical tumour entity has been published in expanded series by the same author as a distinctive tumour of minor salivary glands involving the oral cavity and especially the base of the tongue. Consequently a new name “cribriform adenocarcinoma of minor salivary glands” was proposed (CAMSG). The tumour is locally aggressive with infiltration of the surrounding skeletal muscles, with early metastases to the regional lymph nodes. The treatment of primary lesions consists in local excision, and neck lymph nodes metastases need combined surgical and/or radiotherapeutical approach. This is a case report of CAMSG in a 59-years old woman, without cervical lymph nodes involvement. The patient underwent surgical excision of the primary tumour of the tongue and neck prophylactic radiotherapy. Clinical features of the case are discussed and related to current literature.

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