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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2012 December;171(6):703-11
Biochemical parameters of zinc and activity of superoxide dismutase and glutathione peroxidase enzymes in athletes
Sepúlveda De Andrade Mesquita L. 1, Batista De Sousa Lima V. 1, Machado Moita Neto J. 2, Fransciscato Cozzolino S. M. 3, Do Nascimento Marreiro D. 1
1 Departament of Nutrition, Experimental Nutrition Laboratory, Federal University of Piauí, Teresina, Piauí, Brazil;
2 Department of Chemistry, Federal University of Piauí, Teresina, Piauí, Brazil;
3 Department of Science, Food and Experimental Nutrition, School of Pharmacy, University of São Paulo (USP), Brazil
AIM: The physical exercise induces the oxidative stress, and alterations in the metabolism of zinc and antioxidant enzymes. This study assessed the biochemical parameters of zinc and activity of superoxide dismutase and glutathione peroxidase enzymes in athletes adolescents.
METHODS: Fifty-two male adolescents, aged between 14 and 19 years, were divided in two groups: case group, composed of judoists (N.=25), and control group (N.=27). Were carried out assessement of body composition, food intake and, blood samples were obtained 24 h after training to measure plasma and erythrocyte zinc and activity of superoxide dismutase and glutathione peroxidase enzymes.
RESULTS: The mean of plasma zinc was 72.9±14.6 µg/dL for athletes, and 71.3±15.9 µg/dL for controls, and of erythrocyte zinc was 43.1±11.3 µg/gHb in athletes, and 41.2±8.6 µg/gHb in controls, and of activity of superoxide dismutase was 1,373.2±396.4 U/gHb-athletes and 1,466.6±320.0 U/gHb-controls (P>0.05), and of glutathione peroxidase enzyme was 39.5±10.0 U/gHb for athletes and 55.6±12.4 U/gHb for controls (P<0.05). However, weight, body mass index, lean mass, zinc intake were higher in athletes than control group, and percentage of fat were lower in athletes (P<0.05). The plasma and erythrocyte zinc, as well as activity of superoxide dismutase did not show significant differences between physically active subjects and controls.
CONCLUSION: The results suggest that there are no alterations in the compartmentalization of zinc in adolescent judoists and that the activity of glutathione peroxidase is reduced in athletes in relation to the control group.