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A Journal on Internal Medicine and Pharmacology

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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2012 April;171(2):97-102

language: English

Perioperative blood glucose level in non diabetic patients undergoing on pump versus off pump coronary artery bypass grafting

Kamalipour H., Akhlagh H., Dabiri G., Kamali K.

Department of Radiology, Shiraz University of Medical Sciences, Iran


Aim. Hyperglycemia during cardiac surgery is associated with poor outcomes, more complications and increased mortality not only in diabetic patients but also in patients who are not previously diagnosed with diabetes. The purpose of this study is to compare perioperative blood glucose level in off-pump CABG versus on pump CABG in non diabetic patients undergoing coronary artery bypass grafting.
Methods. One hundred fifty consecutive patients aged 40 to 65 year old, ASA class II or III, ejection fraction 40% or more were enrolled. One hundred enrollees went through on pump cardiac surgery whereas fifty enrollees were operated without cardiopulmonary bypass. Blood glucose level was recorded six times; before induction of anesthesia, after anesthesia induction, before grafting, after grafting, 30 minutes after protamine administration and 1st postoperative hour. Statistical analysis was performed with SPSS software version 15(Chicago, IL, USA)
Results. Both groups showed ascending trend in perioperative blood glucose level but there was no significant difference between them except for post grafting blood glucose(p=0.02). There was an increasing pattern of hyperglycemia from intra operative period (13%) to post operative period (up to 90%) in both on pump and off pump groups but no significant difference was seen between two groups.(p>0.05)
Conclusion. It would be wise to attend to the matter of glycemic control particularly in post grafting phase and post operative phase with specific attention to patients undergoing cardiopulmonary bypass.

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