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Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1812
Cardile A. 1, Francis T. B. 2
1 Department of Internal Medicine, Tripler Army Medical Center, Honolulu, HI, USA
2 Department of Endocrinology, Tripler Army Medical Center, Honolulu, HI, USA
This case report describes two cases of patients with thyroid carcinoma, and one with Graves’ disease, all who had complicating Struma ovarii (SO). We summarize the clinical history, diagnostic studies and treatment of three patients found to have SO with simultaneous thyroid pathology. A 44 y/o female with Papillary Thyroid Cancer (PTC), follicular variant, was incidentally diagnosed with SO on post-ablation scan. A 57 y/o female with PTC, follicular variant, had elevated postsurgical thyroglobulins and an incidental diagnosis of SO by post-ablation scan. A 38 y/o female presented with clinical history and findings diagnostic of Graves’ disease, and an ovarian mass that was increasing in size, with ovarian pathology revealing SO. Clinical endocrinologists must have a high index of clinical suspicion for SO when treating Grave’s disease or thyroid cancer with known ovarian masses of undetermined pathology. Failure to do so increases medical costs, prolongs the resolution for the patient, potentially diminishes the efficacy of I-131 treatment, and places child bearing age woman at unknown risk for ovarian damage.