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A Journal on Internal Medicine and Pharmacology

Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index

Frequency: Monthly

ISSN 0393-3660

Online ISSN 1827-1812


Gazzetta Medica Italiana Archivio per le Scienze Mediche 2011 June;170(3):197-200


Benign focal crises associated with rotavirus gastroenteritis: case report and review of literature

Di Pietro E. 1, Braccili T. A. 3, Capanna R. 3, Di Giovanni G. 2, Perri R. 3, Di Pietro M. 3

1 Department of Child Neuropsychiatry, S. Orsola-Malpighi Hospital, Bologna, Italy
2 Advisor Neurologist, Department of Neurology, G. Mazzini Hospital, Teramo, Italy
3 Department of Pediatrics and Neonatology, S. Liberatore Hospital, Atri, Teramo, Italy

The International League Against Epilepsy Diagnostic Scheme (ILAE) (2001) recognizes two types of benign infantile focal seizures: familial and non familial benign infantile focal seizures. In the new ILAE report these are united in a single syndrome. Seizures are characteristically limited in time and occur in clusters. At least non familial forms may be due to one or more etiological factors.Case of benign infantile seizures associated with diarrhea episodes caused by Rotavirus are reported and its clinical features and outcomes are described. This syndrome is characterized by several criteria: generally it occurs in six-month to three-year-old children who present with afebrile seizure and it is associated with gastroenteritis with mild dehydration, seizures tend to occur in clusters and interictal EEG shows no evidence of paroxysmal discharge; generally laboratory evaluations are no significant, including normal cerebrospinal fluid, serum electrolytes and glycemia. This condition is a benign disease with a good prognosis and self limiting evolution. Investigations must be targeted and anticonvulsivant therapy is not required. Rotavirus is the most common agent. We report the case of a 21-month-old girl that we observed after she had had seizures diagnosed as benign infant convulsions associated with mild diarrhea/enteritis (BICE). We have also reviewed the literature on seizures associated with Rotavirus infections.

language: English


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