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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2010 October;169(5):227-36
Comparation between cervical cytological abnormalities and colposcopy and HPV testing for the prevention the cervical cancer into an adolescential population in Messina, Italia
Pizzo A., Borrielli I., Buda C., Caruso C., Bonanno A. 2, Ardita F., Oteri F., Quattrone S., Giuffrè G. 2, Todaro P. 2
1 Dipartimento Materno-infantile, U.O.C di Ostetricia e Ginecologia, Policlinico Universitario di Messina
2 Dipartimento di Patologia Umana, U.O.C. di Anatomia Patologica, Policlinico Universitario di Messina, Messina, Italia
Aim. The Authors report on results about their surveying on a number of adolescent girls examined at the out-patients’ department devoted to the Gynecology of the infancy and the adolescence at the University of Messina.
Methods. N.588 Pap-Tests was executed on the young girls under examination and the results was compared with those of a population of the same age that underwent the pap-tests some years ago at an out-patients’ department devoted to the prevention of the tumors at the University of Messina.
Results. Cytological abnormalities have emerged to be greater in the population under control for tumors prevention, especially for the cytology classified as ASC-US (20% vs 8%); authors attribute these differences to the methodology employed on the population under examination (liquid based cytology) with respect to the conventional cervical smear employed on the population under control for tumors prevention, and to the different operators analyzing the sample for the patients under control. The patients with cytological abnormalities, under examination at the out-patients’ department for the Gynecology of the infancy and the adolescence, underwent a HPV tiping with biological moleculr methodology; this permitted to reduce the number of colposcopies. According to the literature and in spite of the large number of HPV infections observed, authors have not found CIN 2 and 3. The authors wish to emphasize that their goal in this research, above all, has been the education of the young girls to the periodic control and the screening for the secondary prevention for the cancer pathologies, and to give they information about the more important strategies for the primary prevention.
Conclusion. The authors think that the HPV testing in the adolescent girls is the best second level examination for to make the triage both in the case of ASC-US and in the case of L-SIL, with the aim to examine with colposcopy only the patients with an high risk HPV.