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Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1812
Di Pierro F. 1, Catacchio V. 2, Candidi C. 3, Zerbinati N. 4, Alfonso R. 5
1 Scientific Director, Velleja Research, Pontenure (PC), Italy
2 Anthea Clinic, Bari, Italy
3 ASL, Rome, Italy
4 Dermatology Department, University of Varese, Varese, Italy
5 Gynaecology Department, University of Bari, Bari, Italy
Aim and methods. Aim of this study was the clinical testing of a vaginal tablet containing lactic acid, L. acidophilus and Krameria triandra standardized dry extract in subjects (165) affected by infective vaginal disorders caused by Candida spp., Gardnerella or Trichomonas.
Results and conclusion. The product administered for 10 days (1 tablet per night) treats effectively vaginal symptoms (itch, burning, leucorrhoea), making negative 100% of the vaginal swabs in case of Gardnerella or Trichomonas infection and from 66% to 100% in case of Candida spp. infection (results evaluated 7 days after last tablet administration). Tolerability was good with only 12 cases reporting burning sensation for the first 2-3 days of application. No adverse events or drop outs have been observed.