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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2009 October;168(5):321-5
Overlap autoimmune hepatitis or hepatic sarcoidosis. A case report
Fortis A., Kagmakis P., Mataliotakis M., Kordalis A.
Department of Internal Medicine, Asklepeion General Hospital, Athens, Greece
Here we report on a case of a 54-year-old female patient with hepatitis. Clinical picture and histopathology of the liver were compatible with primary biliary cirrhosis. However a moderately increased Serum Angiotensin Converting Enzyme and hypercalcemia were present. An extensive work up was performed which did not revealed any findings compatible with sarcoidosis. Never the less no antibodies compatible with autoimmune disease were found and all other forms of hepatitis were excluded. Atypical (overlap) autoimmune hepatitis was diagnosed by applying Diagnostic Scoring System. A course of steroids was initiated with impressive results. This group of hepatitis is not clearly defined. We consider that our case represents a form of overlap hepatitis and could give further informations regarding this type of disease.