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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2008 December;167(6):275-81
Serum responses of C-reactive protein and Complement (C3 and C4) to the 6-week preparation period in young professional karateka
Tartibian B. 1, Akbari H. 1, Abbasi A. 2
1 Department of Physical Education and Sport Science, Faculty of Humanities Urmia University, Urmieh, Iran
2 Institute of Sport Science University of Tuebingen, Tuebingen, Germany
Aim. The purpose of this study was to examine the effects of 6-weeks preparation period on a pro-inflammatory acute phase proteins (CRP, complement C3, C4) in young professional male karateka.
Methods. For this purpose, 10 male professional karate athletes with mean (SD) aged 20.8±2 years weight 68±5 kg; height 175±4 cm and body fat 7.6±2%, were enrolled in this study. The athlets performed 6 wk preparation training program for participating in Fajr international karate tournament. Blood sampling was obtained on each subject 24 hours before the training program (Time 1), at end of 3rd week (T2), and at the end of 6th week (T3). Data analysis was conducted by One-way repeated measures analysis of variance (ANOVA) and when significance was found, a Tukey post hoc test was performed.
Results. The serum CRP levels increased nonsignificantly at T2, and returned to baseline at T3. C3 concentration increased at T2 and returned to the normal range at T3, however the changes were non-significant (p=0.712). C4 concentration increased significantly at T2 (18%) and returned to the normal range at T3 (P=0.02).
Conclusion. The results of this study demonstrate that all three proinflammatory acute phase proteins were increased in mid-weeks of training program, representing the activation of acute phase response at this time.