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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2008 August;167(4):153-7
Psychological stress and other pathogenetic co-factors in autoimmune diseases
Pascalis L. 1, Saba L. 2, Pia G. 3, Mallarini G. 2, Becheroni O. 4
1 Reparto di Medicina 2^ Azienda Ospedaliero Universitaria di Cagliari, Presidio di Cagliari, Cagliari
2 Dipartimento di Radiologia Azienda Ospedaliero Universitaria di Cagliari Presidio di Monserrato
3 Pronto Soccorso, Ospedale SS. Trinità ASL 8, Cagliari
4 Consulente psico-filosofico, Cagliari
Aim. To study stress incidence in the development or reactivation of autoimmune diseases as environmental factor directly acting on genetic substrate.
Methods. From September 2006 to September 2007, 400 patients affected by autoimmune diseases have been studied in our Department. For all patients a complete anamnesis was obtained. Patients have been then followed up.
Results. In the study group it was observed a significant incidence of psychological stress and other cofactors in the development or in the pathogenesis of reactivation in several types of autoimmune diseases.
Conclusion. Obtained data resulted encouraging even if the reduced number of enrolled patients in the study could be an important bias. Further studies will be necessary to confirm the study results.